By Lijie Grace Zhang, John P Fisher, Kam Leong
3D Bioprinting and Nanotechnology in Tissue Engineering presents a close creation to those applied sciences and their business functions. Stem cells in tissue regeneration are lined, in addition to nanobiomaterials. Commercialization, felony and regulatory concerns also are mentioned for you to assist you translate nanotechnology and 3D printing-based items to and the health center. Dr. Zhang’s and Dr. Fishers’ workforce of professional individuals have pooled their services which will offer a precis of the suitability, sustainability and obstacles of every procedure for every particular program. The expanding availability and lowering charges of nanotechnologies and 3D printing applied sciences are using their use to fulfill scientific wishes, and this ebook presents an summary of those applied sciences and their integration. It indicates how nanotechnology can elevate the medical potency of prosthesis or man made tissues made by way of bioprinting or biofabrication. scholars and pros will obtain a balanced evaluate of suitable know-how with theoretical starting place, whereas nonetheless studying concerning the most recent printing techniques.
- Includes medical purposes, regulatory hurdles, and risk-benefit research of every technology.
- This ebook will help you in choosing the right fabrics and making a choice on the correct parameters for printing, plus comprise cells and biologically lively brokers right into a revealed constitution
- Learn the benefits of integrating 3D printing and nanotechnology so that it will increase the security of your nano-scale fabrics for biomedical applications
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Extra resources for 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
Based on the basic concept just mentioned, Zhang et al. , 2012). 4. , 2012). , 2012). , 2013), which has been used to produce nanoscale features due to its high fidelity and resolution. 2PP systems usually utilize a femtosecond laser to induce two-photon absorption (2PA). 2PA is a process by which one molecule is excited to a higher energy electronic state by the simultaneous absorption of two photons (Zhang and Chen, 2011). 2PA was described theoretically in 1931 by Goeppert-Mayer (Göppert-Mayer, 1931) and first demonstrated experimentally in 1961 by Kaiser and Garrett (Kaiser and Garrett, 1961) in a CaF2:Eu2+ crystal, and in 1962 by Abella in caesium vapor (Abella, 1962).
The biomaterials with cells are referred to as “matrix”. The substrate, similar to the “collector-slide”, may or may not be covered with hydrogel. Laser is focused on the interface of the quartz support and a laser-absorptive layer containing cells. The laser beam causes evaporation of part of the biomaterial layer, which generates gas bubbles locally. The gas bubbles result in the release and propulsion of the cell-seeded matrix to the receiving substrate. , 2004). 5 BIOLOGICAL LASER PRINTING Biological laser printing (BioLP) was developed by Barron et al.
It can catalyze the hydrolysis of phosphate esters at alkaline pH and influences on the bone matrix mineralization. ALP activity kept increasing until 7 days after seeding, but decreased between 7 days and 14 days. , 2006). There was no significant difference in cell proliferation and ALP activity between two nanocomposite scaffolds. , 2009). PLA powder mixed with carbon black was sintered with a continuous wave fiber diode laser having an energy density of about 100 ± 20 W/cm2. The scan speed was 3 mm/s.